New: Advanced laser microtomy for plastic embedding is operational , Digital Pathology AI methods are in continuous development , GLP accreditation for the following two years 2024-26 , We will present a scientific work in CNS pathology during the ESTP meeting 2024 in Madrid

News

ISO 10993: Ensuring biological safety of medical devices in the context of the histopathological tissue...
Advanced Laser Microtomy for the dissection of plastic embedded hard tissues such as bones and...
Methodological Aspects of Advanced Laser Microtomy for plastic embedded tissue and materials   Dr. Emmanuel...

Services

Toxicity Services
Pathology & Toxicology Services
Consulting Services & Tailored Solutions
Pre-Clinical Trials Management Services
Feasibility Studies

Major fields of expertise

Central Nervous System

Central Nervous System

CNS models based on knowledge of the pathological mechanism of human diseases for ALS, Alzheimer’s disease, BBB Permeability, Epilepsy, Multiple Sclerosis, Parkinson disease, Stroke, Traumatic central and spinal cord injury, and Vascular dementia.

Oncology

Oncology

Treatments are tested in appropriate solid and metastatic tumor models related to the human tumor type, which include Blood (leukemia), Bone, Brain, Breast, Cervix, Colon, Liver, Ovary, Pancreas, Prostate, Skin (melanoma), and Urinary bladder.

Medical Device Histopathology Analysis

Medical Device Histopathology Analysis

We purchased a novel laser microtomy for the dissection of plastic embedded materials that includes hard tissues and medical device implants such as tooth implants, orthopedic devices, tissue engineering devices and scaffold.

Stem Cells

Stem Cells

We are involved in many studies in this new developing field. Uses of stem cells include regenerative medicine in central and peripheral diseases, for which we have experience in models of Cardiovascular, Diabetes, Hind limb ischemia (angiogenesis), Multiple sclerosis, Osteoarthritis, Parkinson’s disease, Spinal cord injury, Stroke, Traumatic brain injury, and Wound healing.

Inflammation Immunology

Inflammation Immunology

Acute models include Carrageenan-induced paw edema and Formalin-induced acute inflammation. Chronic models include Inflammatory bowel disease, Multiple sclerosis (EAE). Osteoarthritis, and Rheumatoid Arthritis. Immunological models include LPS stimulation of murine macrophage cells. Studies employ immunohistochemistry tools for cellular identification and quantification.

POC (proof of concept)

POC (proof of concept)

These unique studies use the candidate treatment in a small experiment employing advanced technological tools as special markers and image analysis capabilities.

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